Syntheses of trans-SCH-A and cis-SCH-A via a stereodivergent cyclopropanation protocol.
Csatayová K., Davies SG., Lee JA., Ling KB., Roberts PM., Russell AJ., Thomson JE.
A highly diastereoselective cyclopropanation protocol has been employed in the syntheses of trans-SCH-A and cis-SCH-A. This strategy encompasses a stereodivergent procedure for the preparation of syn- and anti-cyclopropane diastereoisomers in high dr from a common allylic carbamate precursor.