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Publications

Microperimetry as an Outcome Measure Improves Patient Eligibility and Efficacy Detection in RPGR Gene Therapy Trials

JOSAN AS. et al, (2026), American Journal of Ophthalmology, 290, 61 - 69

Accurately modeling RNase H-mediated antisense oligonucleotide efficacy.

Hill B. et al, (2026), Mol Ther Nucleic Acids, 37

Centripetal Retinal Degeneration Follows an Exponential Decay and May Be Reversed Following Gene Therapy

ABDALLA  ELSAYED MEA. et al, (2026), American Journal of Ophthalmology, 289, 76 - 86

Timing matters: Exon skipping therapy is most effective when initiated early in a mouse model of Duchenne muscular dystrophy

Stenler S. et al, (2026), Molecular Therapy Nucleic Acids, 37, 103017 - 103017

α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.

Lam CL. et al, (2026), Nat Commun, 17

Interactions Between Epidermal Growth Factor–Containing Fibulin-Like Extracellular Matrix Protein 1 and Tissue Inhibitor of Metalloproteinases-3 and Relevance to Age-Related Macular Degeneration

Ehrenzeller C. and MacLaren RE., (2026), Ophthalmology Science, 6

Cell–cell adhesion cannot sustain extended follower streams in a minimal non-local model of leader–follower migration

Jewell T. et al, (2026), Journal of Theoretical Biology

The Thrombopoietin Receptor S264F Mutant Drives MPN with Marrow Fibrosis Through a Dual Mechanism

MEAD A., (2026), HemaSphere

An energy-based mathematical model of actin-driven protrusions in eukaryotic chemotaxis

Samuel J. et al, (2026), Biophysical Journal

Resolving hematopoietic stem versus progenitor cell potential in the mouse dorsal aorta by differential Runx1 +110 enhancer activity.

Anselmi G. et al, (2026), Cell Rep, 45

Circulating protein profiling identifies prognostic biomarkers in amyotrophic lateral sclerosis

Klimovski H. et al, (2026)

The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.

Boucher AC. et al, (2026), Leukemia

Patient experiences of tissue donation and digital consent support in primary craniospinal tumour research.

Mawhinney G. et al, (2026), Support Care Cancer, 34

Presynaptic SNAP25 supports maturation of hippocampal mossy fiber-CA3 synapses.

Hayashi S. et al, (2026), iScience, 29

Deletion of Snap25 disrupts glial remodeling in aging mouse brain.

Vadisiute A. et al, (2026), iScience, 29

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