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The range of genetic diversity within human populations is enormous. Genetic susceptibility to common chronic disease is a significant part of this genetic diversity, which also includes a variety of rare clear-cut inherited diseases. Modern DNA-based genomic analysis can now routinely lead to the identification of genes involved in disease susceptibility, provides the basis for genetic counselling in affected families, and more widely for a genetically targeted approach to disease prevention. This naturally raises problems concerning the use of information on an individual's decisions, but for employment, and health and life insurance.

Original publication

DOI

10.1098/rstb.1997.0083

Type

Journal article

Journal

Philos Trans R Soc Lond B Biol Sci

Publication Date

29/08/1997

Volume

352

Pages

1045 - 1050

Keywords

Genetic Diseases, Inborn, Genetic Testing, Genetic Variation, Humans