"Pure by NMR"?
Claridge TDW., Davies SG., Polywka MEC., Roberts PM., Russell AJ., Savory ED., Smith AD.
Integration of a (13)C-(1)H satellite peak of a given (12)C-(1)H parent resonance within a quantitative (1)H NMR spectrum and comparison to the minor component represents a simple protocol for the accurate determination of diastereoisomeric ratios of up to 1000:1 (i.e., 99.8% de).