Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Mathematical models to describe the diffusion of single cryoprotecting agents (CPA) and multiple CPAs in tissue contructs were developed. Fick's law was used to describe single CPA diffusion, and Maxwell-Stefan approach was used to describe multiple CPA transport inside the tissue. The model used to to stimulate the CPA loading in articular cartilage and blood vessel constructs. Experimental work using diffusion chambers was carried out to determine the model parameters and verify the models.


Journal article


Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products

Publication Date