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Prominent choroidal atrophy is a feature of multiple inherited retinal disorders with choroideremia as the classic and most commonly encountered example. In this chapter, we review the genetic and clinical features of choroideremia, gyrate atrophy, and other hereditary conditions manifesting with choroidal atrophy with discussions of underlying mechanisms and potential therapies as relevant.

Original publication





Book title

Albert and Jakobiec's Principles and Practice of Ophthalmology: Fourth Edition

Publication Date



3997 - 4012