Choroideremia and Other Hereditary Conditions Manifesting with Choroidal Atrophy
Song WK., Cehajic-Kapetanovic J., Patrício MI., Xue K., MacLaren RE.
Prominent choroidal atrophy is a feature of multiple inherited retinal disorders with choroideremia as the classic and most commonly encountered example. In this chapter, we review the genetic and clinical features of choroideremia, gyrate atrophy, and other hereditary conditions manifesting with choroidal atrophy with discussions of underlying mechanisms and potential therapies as relevant.