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BACKGROUND: Robenacoxib is a novel and highly selective inhibitor of COX-2 in dogs and cats and because of its acidic nature is regarded as being tissue-selective. Thirty four dogs with stifle osteoarthritis secondary to failure of the cranial cruciate ligament were recruited into this study. Lameness, radiographic features, synovial cytology and C-reactive protein concentrations in serum and synovial fluid were assessed before and 28 days after commencing a course of Robenacoxib at a dose of 1 mg/kg SID. RESULTS: There was a significant reduction in the lameness score (Pā€‰

Original publication

DOI

10.1186/1746-6148-9-42

Type

Journal article

Journal

BMC Vet Res

Publication Date

01/03/2013

Volume

9

Keywords

Animals, C-Reactive Protein, Cyclooxygenase Inhibitors, Diphenylamine, Dog Diseases, Dogs, Female, Lameness, Animal, Male, Osteoarthritis, Phenylacetates, Radiography, Stifle, Synovial Fluid