Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Bunyamwera virus and snowshoe have virus (family Bunyaviridae) were passaged up to six times through mosquito cells in culture and the resultant viruses were compared to the input, mammalian cell-passed virus using monoclonal antibodies raised against the input virus. The mosquito cell-adapted virus population consisted of mutants which were better adapted to replication in the new host than was the input mammalian cell-passed virus and were differentially susceptible to neutralization by antibody.

Original publication




Journal article


J Gen Virol

Publication Date



67 ( Pt 12)


2803 - 2806


Aedes, Animals, Antibodies, Monoclonal, Antibodies, Viral, Antigens, Viral, Bunyamwera virus, Bunyaviridae, Cell Line, Chlorocebus aethiops, Epitopes, Genes, Viral, Mutation, Neutralization Tests, Viral Envelope Proteins, Viral Plaque Assay, Virus Replication