Kinetic resolution of the chiral iron acetyl [Fe(η5-C 5H5)(CO)(PPh3)COMe]
Case-Green SC., Costello JF., Davies SG., Heaton N., Hedgecock CJR., Prime JC.
The chiral discrimination displayed between the enolate derived from (RS)-[Fe(η5-C5H5)(CO)(PPh3)COMe] and (1R)-(+)-camphor furnishes a practical route to homochiral (R)-[Fe(η5-C5H5)(CO)(PPh3)COMe] via a kinetic resolution protocol, while a retro-aldol reaction of the diastereoisomerically pure aldol addition product of this kinetic resolution sequence provides a complementary route to the opposite enantiomer (S)-[Fe(η5-C5H5)(CO)(PPh3)COMe].