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The pro-R hydrogen of (+)-N,N-dimethylamphetamine chromium tricarbonyl can be stereospecifically substituted via sequential treatment with BunLi and an electrophile, with retention of configuration to give for example N-methylpseudoephedrine after decomplexation.

Original publication

DOI

10.1039/c39850000653

Type

Journal article

Journal

Journal of the Chemical Society, Chemical Communications

Publication Date

01/01/1985

Pages

653 - 654