Chiral relay effects influence the facial selectivity of N-alkylated 5- phenylmorpholin-2-one enolates
Bull SD., Davies SG., Fox DJ., Sellers TGR.
Alkylation studies on the enolate of N-methyl morpholinone 7 clearly reveal that the observed cis-selectivity is consistent with a chiral relay system operating to invert the stereochemical information of the auxiliary's C5 stereogenic centre.