Synthesis and reactivity of a range of 2-ferrocenyl-3-pivaloyl-1,3-oxazolidin-5-ones
Alonso F., Davies SG., Smethurst CAP.
A range of novel 2-ferrocenyl-3-pivaloyl-1,3-oxazolidin-5-ones has been synthesised, both with and without 2-substitution on the ferrocenyl moiety in an effort to develop an asymmetric glycine equivalent. While C-4 alkylation of the parent complex 2-ferrocenyl-3-pivaloyl-1,3-oxazolidin-5-one was successful, the presence of a 2-substituent on the ferrocene ring has been found to prevent C-4 enolisation and hence alkylation.