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An asymmetric synthesis of homochiral α-amino acids has been developed which is based on the conjugate addition of organocuprates to the dehydroalanine equivalent (3S)-N,N′-bis(p-methoxybenzyl)-3-isopropyl-6-methylenepiperazine-2,5-dione 6.

Original publication

DOI

10.1039/a807618i

Type

Journal article

Journal

Journal of the Chemical Society - Perkin Transactions 1

Publication Date

21/11/1998

Pages

3657 - 3658