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An alternative strategy for chiral auxiliary design is described where configurationally flexible moieties are employed to relay, inert, and amplify the stereochemical information of existing stereogenic centres via chiral relay networks, thus ensuring efficient control of asymmetric induction.

Original publication

DOI

10.1351/pac199870081501

Type

Journal article

Journal

Pure and Applied Chemistry

Publication Date

01/01/1998

Volume

70

Pages

1501 - 1506