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A concise route to the core fragment of sperabillins B and D, methyl (3R,5R,6R)-3,6-diamino-5-hydroxyheptanoate, has been developed with a subsequent novel protection strategy allowing the total asymmetric synthesis of sperabillins B and D.

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

07/09/2003

Pages

2132 - 2133