Emerging In Vitro 3D Tumour Models in Nanoparticle-Based Gene and Drug Therapy.
Wong JK., Seifalian A., Mohseni R., Hamidieh AA., MacLaren RE., Habib N., Seifalian AM.
3D models are emerging as valuable tools for personalised nanoparticle-based cancer treatments. 3D models represent in vivo cancers more realistically than 2D patterns that are grown in Petri dishes. However, creating a 3D cancer model that mimics the complexity and heterogeneity of cancers in vivo remains difficult.