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The capacity to harness the properties of pluripotent stem cells has a wide-reaching impact on regenerative medicine, drug discovery, and also basic science. Two recent publications by Ursu et al. and Illich et al. demonstrate that inhibition of a CK1 isoform efficiently induces naive pluripotency in epiblast stem cells.

Original publication

DOI

10.1016/j.chembiol.2016.05.002

Type

Journal article

Journal

Cell Chem Biol

Publication Date

19/05/2016

Volume

23

Pages

532 - 534

Keywords

Germ Layers, Pluripotent Stem Cells, Signal Transduction