Molecular basis for mild forms of homozygous beta-thalassaemia
Weatherall DJ., Pressley L., Wood WG., Higgs DR., Clegg JB.
Five Cypriots homozygous for beta +-thalassaemia have inherited deletion or non-deletion forms of alpha-thalassaemia that seem to have modified the usually severe clinical picture to that of mild thalassaemia intermedia. These observations have important implications for the antenatal diagnosis of beta-thalassaemia.