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A novel arylsilane based linker has been prepared for the solid phase synthesis of small molecule combinatorial libraries. Efficient cleavage is achieved using TFA via anchimerically assisted protiodesilylation to yield aromatic products possessing no residual linker functionality.

Original publication

DOI

10.1016/S0040-4039(97)10650-5

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

19/02/1998

Volume

39

Pages

897 - 900