Chiral relay auxiliary for the synthesis of enantiomerically pure α-amino acids
Bull SD., Davies SG., Epstein SW., Ouzman JVA.
Chiral auxiliary (3S)-N,N′-bis(p-methoxybenzyl)-3-iso-propylpiperazine-2,5-dione employs a chiral relay network based on non-stereogenic N-benzyl protecting groups to enhance diastereocontrol during enolate alkylation.