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The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-amino-cyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-alpha-methylbenzylamide.

Original publication

DOI

10.1039/b209728c

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

07/12/2002

Pages

2910 - 2911