Ruth Baker
Professor of Applied Mathematics
Research interests
My research focuses on developing and applying novel mathematical, computational and statistical methodologies and modelling frameworks for investigating developmental biology systems at the cell and tissue level. I develop biologically realistic models that, used in tandem with experimental investigations, can provide fundamental insights into key biological mechanisms. An important aspect of my work is therefore multidisciplinary collaboration with theoreticians, life scientists and clinicians both within Oxford and further afield.
I also play a key role in QBIOX (https://www.qbiox.co.uk/), an MPLS-funded initiative to develop quantitative biology in Oxford.
Prizes, awards, and scholarships:
- Royal Society Wolfson Research Merit Award 2017-2022
- Leverhulme Research Fellowship 2017-2019
- London Mathematical Society Whitehead Prize 2014
Recent publications
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Modeling cell differentiation in neuroblastoma: insights into development, malignancy, and treatment relapse
Journal article
Martina Perez S. et al, (2025), Journal of Theoretical Biology
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Modelling collective cell migration in a data-rich age: challenges and opportunities for data-driven modelling
Journal article
Baker R. et al, (2025), Cold Spring Harbor perspectives in biology
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Optimal control in combination therapy for heterogeneous cell populations with drug synergies
Journal article
Martina-Perez S. et al, (2025), Bulletin of Mathematical Biology
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Modelling the impact of phenotypic heterogeneity on cell migration: a continuum framework derived from individual-based principles
Journal article
Crossley R. et al, (2025), Bulletin of Mathematical Biology
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Mathematical modelling predicts novel mechanisms of stream confinement from Trail/Colec12/Dan in the collective migration of cranial neural crest cells
Journal article
Johnson S. et al, (2025), Developmental Dynamics