Ji-Long Liu
Intracellular compartments such as organelles are essential for a cell’s function. RNA occurs in every compartment in a cell. Research in the Liu group focuses on three fundamental questions relating to RNA, for which we seek an in vivo understanding. We choose the fruitfly Drosophila melanogaster as our prime model system because of its genetic tractability and the depth of genomic data. Studies in Drosophila have provided a key to vertebrate development and human biology.
Recent publications
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Cytoophidia respond to nutrient stress in Drosophila.
Journal article
Wu Z. and Liu J-L., (2019), Exp Cell Res, 376, 159 - 167
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Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants.
Journal article
Zhang W. et al, (2019), Dev Cell, 48, 406 - 419.e5
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mTOR-S6K1 pathway mediates cytoophidium assembly.
Journal article
Sun Z. and Liu J-L., (2019), J Genet Genomics, 46, 65 - 74
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Forming cytoophidia prolongs the half-life of CTP synthase.
Journal article
Sun Z. and Liu J-L., (2019), Cell Discov, 5
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Filamentation of asparagine synthetase in Saccharomyces cerevisiae.
Journal article
Zhang S. et al, (2018), PLoS Genet, 14