Asymmetric syntheses of fagomine and its stereoisomers

Davies SG., Fletcher AM., Roberts PM., Thomson JE.

D-Fagomine (1,2,5-trideoxy-1,5-imino-d-arabino-hexitol), a naturally occurring polyhydroxylated piperidine (iminosugar), and its stereoisomers display important biological activities such as glycosidase inhibition. This review delineates both de novo asymmetric and enantiospecific syntheses of fagomine and its stereoisomers.

DOI

10.1016/j.tet.2019.130727

Type

Journal article

Publication Date

2019-12-13T00:00:00+00:00

Volume

75

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