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Electrospinning, a micro/nanoscale fiber-forming process, and electrospraying, a micro/nanoscale particle-forming process, have gained tremendous attention in the recent years in the biomedical field. The resultant micro/nanomaterials are being used as matrices in tissue engineering and regenerative medicine, carriers in drug delivery, sensory systems in biosensing, contrasting agents in bioimaging, and smart and intelligent human-machine interface systems. The instrumentation has evolved from bench side to commercial as well as point-of-care devices. Further, electrospun/electrospray medical devices have started to get through the clinical trials and regulatory clearances in recent times. The field has also seen innovative cross-disciplinary developments in combination with three-dimensional printing, microfluidics, etc. This chapter offers a retrospective view on the technological advances in electrospinning and electrospraying, followed by applications of electrospinning/spraying materials in biomedical field, highlight developments in the electrospinning/spraying units, including lab-scale, large-scale and point-of-care devices, throws light on the transformation of e-spun/e-spray materials into human-machine interface systems, and finally highlights the future prospects in the field toward successful translation from bench to bedside.

Original publication





Book title

Biomedical Applications of Electrospinning and Electrospraying

Publication Date



375 - 393